I just recently come off of Lithium 450mg per day (my choice) and I still fill fine. I have back problems and I can't take anything with lithium to reduce inflammation or relive pain. I have also been on lamictal 100mg per day for a little while now. Seem to be doing ok with dropping lithium. Just hope pdoc will be ok with it, she did want to try dropping some of my starter meds, but when she first mentioned it I about freaked out .