Prozac killed my sex drive and made it really hard to have an orgasm even alone. I still had sex, but it was more because I wanted to make her happy than I "needed" it. On wellbutrin it is sort of the opposite effect than Prozac. I don't have more of a desire than normal, but I get there faster, which for me isn't a bad thing since before the meds it used to take a little while to finish.

I'm sure meds have a different effect on everyone though.