I have degenerative disk issues throughout my whole spine, a prolapsed one an two herniated ones too causing three nerves to be impinged sligtly and some muscles around my spine to be weakened too, as my legs don't work i have no choice but prolonged sitting, i find co-codamol 30/500 along with a high setting tens machine to be the best relief from the pain. swimming also helps even though it is just my arms propelling me