I don't intend to breed a mistrust of doctors, but I think in dealing with them it can be healthy to hold a certain sense of skepticism.

I've been diagnosed Bipolar since 2007 and in that time I've dealt with five different psychiatrists. A few of them had a tendency to throw as much drugs as they could at the problem, because, more, not less drugs, is likely to solve the main issue, just as a side effect they tend to cause a lot of other side effects, like what you've mentioned (lethargy, depression). Back in about 2009 I had a psychiatrist diagnose me 125 mg Seroquel 3x a day. For one fill of the prescription it cost about 200 dollars without health insurance. I took just one of those pills and it knocked me right out; after that I refused to take them regularly and it turned out that I ended up quite fine on the medication I was already taking.

The moral of the story? Doctors, psychiatrists, are not God-like, all-knowing medical wizards who always make the right decisions, and in fact, given the complexity of dosage/gene interaction, the prescribing of medication isn't far off of a pseudo-science. And so, as I began the post, it's healthy to have a sense of skepticism when dealing with your doctors decisions. It is also extremely important to keep a very close watch on your mood and behaviour through the days and weeks. If you're feeling manic, depressed, lethargic, or some other life-inhibiting side-effect, it's likely that you need to talk to your doctor and suggest a change.

This is not all to say that you should mistrust your doctor, but you should realize that, once you're well educated on your disorder, you need to be pro-active in the psychiatric/patient relationship and not blindly accept everything your doctor tells you.