I'm 40 yrs old & have suffered with depression all my life. In the beginning I tried many different medicines also. They would seem to work in the beginning but it would never last. I too got tired of all the nasty side affects. So I weaned myself off & haven't used anything in over 10 years. I just don't trust any of them. I do still deal with my depression on a daily basis. I just keep pushing myself to get through each day. Some days are better than others.