You're not on Seroquel strictly for sleep, are you?

There are other options to help you sleep. Melatonin, Trazadone, sleeping pills....etc.

I still have nights that I have more trouble falling asleep, too. I wouldn't be too worried unless it continues and continues. Everyone has their up and downs when it comes to sleep. Sometimes this is a sign I'm going into a hypomania/anxiety phase.

[Been on Seroquel for years.]