Don't know about the weakness. I was on Depakote & didn't have any side effects except it didn't really help with the depression. It did help with the agitation (I was in a mixed episode). I did elect to find a new doc when he wouldn't switch me to something else. I was still depressed!

New doc put me on Abilify & Lamictal as well as anti anxiety drug, one to help me sleep & one for ADD. My dx is bipolar 1.

Hope your doc is responsive to you & your concerns. I would notify him immediately of your symptoms. Take care.--Suzy