I was on zyrexa for about 2 yrs and loved it!

Unfortunately, I was/am one of those patients who drop some meds when I begin to feel better....... bad idea.

Though I did have a slight weight gain, it really made a difference in my depression and I am sorry that I decided I didn't need it.... I am now on another atypical and it is working ok.

Good luck and let me know how you do! And remember, watch your carb intake...