My orgasms are incredibly short on meds and less pleasant...now that I'm getting off meds things are getting better however they aren't like they were but I'm still on a low dose. There is no permanant damage it's just that orgasm requires dopamine and that's what the meds block. Some of the meds like risperidone or the older APs cause an increase in prolactin that can also suppress sex drive so that's correctable by switching meds.