Well first...

Holy pharmacy! That's a lot of meds. As an aside, if you are getting along with the Saphris, you are the first person I've heard of that can.

I hear ya on the anxiety part. The only time I used to have anxiety was when I had to fly somewhere. I could usually handle that with a couple of shots of Wild Turkey. Now, my anxiety can last for half a day or more, mostly for no reason. And when I say anxiety, I mean the kind that has me mostly non-functional. In a bizarre way, I get depressed because I am anxious about getting depressed. I usually try to suffer through it because I don't want to start relying on Klonopin to get me through the day.

I posted this before, but my doctor said that bipolar "ages," meaning that it gets more pronounced the older you get. I am 56, and I had mine pretty well under control until 4 years ago when I completely went off the reservation. I have to agree with him. Over the last four years, my ups and downs have become decidedly more pronounced.

Being a male, I can't really comment on the menopause thing.