Hi Meveret

Something occurred to me as I was reading your posts.
You mentioned having severe acne. I can definitely relate to that. Mine used to be so bad I went on a course of antibiotics like three times in a year. It would improve for a little bit and then just get worse again. And I was trying everything I coiuld think of to help it improve. But it was very bad.
Also, that you are overweight. This has always been a problem for me, since... I'm not sure there's a since...

So, I started figuring some things about my diet, because it got to the point where I just felt generally "meh", physically. Occasinally I would feel much worse, on very rare occasions it was like the planets aligned and I felt ok.

I discovered I am at least pretty intolerant to gluten. The stool test I did [this was a WHILE ago, and they didn't do a blood test] came back inconclusive for straight up celiac.

Buit there was a clear correlation- my skin cleared up so much. It's to the point where sometimes people mention that it's actually nice [which still kind of shocks me], I actually lost a HUGE amount of weight that year when i adopted the GF diet and my body felt kind of happy. I was sleeping better and after a short time I didn't really crave junk. my mood did improve a bit as well.

I guess i wrote this huge long obnoxious post just as... I mean it's not always going to be a med change that makes the difference?
And if you are having so much physical stuff, maybe you could explore what is going on with that at an appointment with your GP/PCP?

I'm not trying to diagnose you, but perhaps there is something going on that you've missed?

Anyway, sorry things are so frustrating.