I was on lithium and seroquel but I got lithium toxicity and can't take it. For at least 4 + years I took seroquel, prozac, and klonopin. But last February I had a psychotic episode and spent three weeks in the hospital. They stopped the prozac and put me on depaoke. I never had the slugginess or sleeping issues with it but it causes weight gain. Not sure I want to stay on it.