Hi there. It sounds like that Depakote didn't do well for you so I wouldn't go back on it. I like the suggestion of doing some research about new available drugs and then seeing what you PDOC suggests. Lots of good suggestions in here. I learn something everytime I read a new posting. I sure hope you find what works for you. It sure is a balancing act and everyone has to find the right cocktail to work for them. Good luck and keep us all posted on how you do!