In czech we call it "sould disorder/illness" and I think it's pretty fitting.

Something effecting your soul. My brain is pretty sharp and smart, not broken. My soul, hower has quite a few scars.

And I would not trust the "physical proof, any decade now". They been saying it for decades. Time to admit we don't know some things, that psyche works in strange ways... and maybe it's problem elsewhere, where the brainscans and bloodtests don't reach. So maybe we shouldn't waste time scanning brains of troubled folks, but try to see how to help them right now, within this imperfect society which humans are not really fit for.