I have done this 100% successfully, I now only take natural supplements to help with depression (do NOT do this however without your doctor's advice and approval).

I used supplements and herbs to help with the detox (I was on a pretty nasty drug)...I recommend protein powder and Omega-3s (both help tremendously with brain zaps -- I can't stress these two things enough. For the former I used raw vegan powder and the latter I used cold-pressed flaxseed oil). I recommend time off of work/ school, exercise (even if you have to force yourself), lots of naps and things to distract (books, dvds, good friends). I recommend chamomile tea to help with anxiety...

Of course everyone is different and your doctor can help you by tapering slowly to reduce withdrawal. Make sure to discuss all supplements with your doctor too. It is possible, I have done it. I think everyone is different and it depends on the type of meds you take. Good luck!