One girlfriend of mine, who lives at a distance now, but also on Facebook, takes them and she has done really well with them, both physically and visually. Don't think it's been cheap tho or that in her case insurance has covered much. She's been doing this for about five years and can afford it and watches her health. She looks amazing. She got interested in it from reading Suzanne Sommers but I know has also done some more scientific research. I understand that compounding bioidentical hormones are coming more into mainstream medicine now, as well. Good luck, sorry I don't know any more than that!