Low dose Effexor XR (eg. 37.5mg daily) is effective in controlling neuropathic pain. In general, I do not think that Effexor XR works as well as the tricyclics (Elavil™ - amitriptyline or Aventyl™ - nortriptyline) for this indication, but Effexor XR has a much better side effects profile.

Effexor XR is a very effective antidepressant and, if taken properly, is a very safe drug. That being said, no drug can be designed that would work for everyone. Genetic variability is the reason that people may experience some adverse effects from a drug, but one never experiences all possible side effects. As well, some people are more sensitive to the effects of a drug than are others. Most of the side effects attributed to Effexor XR can be managed using various interventions.

Never fear medications, respect their effects. Certainly, I do see a lot of anti-Effexor XR postings on the internet. I do believe that educating oneself about how the medication that they are taking works is very important. It upsets me to see posts that may frighten someone away from trying a very effective medication that could potentially save their life. Effexor XR has saved many more lives than it has taken.

Just my informed opinion - Cam