I too have been on numerous drugs & combinations for over 21 yrs. some helped for a bit but then stop. Had the most success (8 yrs) w/ a drug combo that included concerta which basically has a cocaine like substance in it. I built up a tolerance to it & it made me very irritable. Also had a bit of w/draw from it.
I've tried ECT & didn't have much luck. Yes it has improved & has become more focused but still does the same thing. My one Pdoc said it was like trying to jump a car w/ electricity to breath new life into it. I get the idea, but it didn't produce anything besides some memory loss. I am not looking into TMS but bec it's so new I know insurance won't cover it. I've asked my Pdoc to think outside the box when he comes up w/ the next combo bec right now I'm on rock bottom again.
Keep pushing for something. Be your own advocate bec no one else really will be.
Good luck!