I can only take a very low AD or I'll flip into full all out psychotic mania. Depression for me isn't bad I usually go into a mixed mania. My baseline naturally is high, and my husband's is naturally low. This means his AD is high. It took me going through most classes of AD's to find one that didn't flip me into mania. I would never allow any of my loved ones go to a pdoc that doesn't allow AD's. To me bipolar is a two part problem that needs to be treated mania and depression. If one part is not being treated then bipolar is not being treated.