Unfortunately it takes time to find the right cocktail of meds and everyone is different.

It was Zoloft that sent me into my first manic episodes many years ago. Depression is a major problem for me. I alter my meds slightly based on my mood. I think based on what I have read this is unusual.

Lamictal is the only steady med I take all the time. When the depression comes on, I slowly add Lexapro and continue to take it as long as the dark mood is present. When I start to feel better and have more energy, I taper off the Lexapro to avoid mania.

When I start cycling up into hypo mania I add seroquel.

That is what works for me. My depression is a big issue, much more dangerous for me than the mania.

Good Luck. Getting a diagnosis is the first step.