Bipolarnurse, I guess thats what confuses me, I started on seroquel in Oct 10 in the hospital and took it until Jan 12 when I switched to saphris which I continue to take. I havent had a major episode of any sort in these past few years until this past spring and that would not have gotten so bad if not for my anxiety going through the roof. I would credit the lack of episodes to continual use of the AP. I believe I started the anxiety problem this spring myself with the use of caffeinated diet pills in Feb, it just snowballed from there. Lesson learned there folks.