I have been on Lamictal for more than four years now. I have experienced almost no side-effects from it. As is common with many diagnosed with bipolar disorder, to have the tendency to swing into mania when taking antidepressants, I too had to be taken off of them long ago. (Wellbutrin sends me up the wall with only two doses. Most of the others accomplish it within 24 hours.)

The sole drawback of Lamictal is that it is neither effective, nor approved by the FDA, for the treatment of mania. So far, my psychiatrist and I have not found much to handle that side of the disorder--not that works for me, that is. But, we keep trying. I haven't given up. Just having the depressive episodes decreased to a minimum, compared with years ago, is gold, as far as I see it.