Absolutely!! I dis-connect the most with the closest people to me!! My family!! There is nothing you can do about it, either, when you are going through it. It is a very scary feeling.
Is she on any anti-depressants? I am on two now and I don't have that depression like I use to.
Just be there when she needs you and you will be fine. I hope she comes out of it soon.
Take care and you are great for being so concerned.
Linda