I'll be on it for my whole life (major depressive disorder aka clinical depression). So I'm not too worried about it. We tried to stay away from it, but none of the normal SSRI's worked. They just left me numb, stupid and anorgasmic. Venlafaxine at least lets me have emotions and function sexually and since I'll be on it for the rest of my life anyway ...

But yeah, coming off of it is hell.