I will tell you I have an Integrative physician I have been seeing for a couple of years. He works in holistic and main stream medicine. He did a blood test on me and specifically asked that my adrenals and thyroid be checked. He is the one that told me I have low adrenals. He explained that having that complicates Bi-polar especially in the manic phase as when it is over your adrenals have nothing to give and you collapse from exhaustion/depression. This doctor is the one who suggested an Orthomolecular Psychiatrist (treats patients on a cellular level) due to the fact that this new doc will do the hormone and gland test for adrenals, etc.. It is a saliva test and blood test. For some odd reason, it has only been within the last few months that I have had such extreme and severe symptoms that put me in the hospital, so I am anxious to see what this new doc comes up with. I am extremely glad to read that someone else relates to my experiences with physical symptoms. From what I am more and more understanding, just having low adrenals will make havoc on your entire system. Then add Bi-polar, Panic attacks, or Fibormyalgia and it is debilitating. Like I said in a previous email anything I can share with anyone from this new doc I will.