I don't have the greatest of voices either - it's rather high for a guy. Speaking slowly and assuredly makes my voice sound better. Also, what you say is more important than how it sounds. If you have something to say then people will be more apt to listen. So, choose your words carefully.

You seem to be very intelligent but have a radical approach to things that make you stand out as strongly un-conformist. Use your intelligence to find commonality with people rather than make you stand out as too different for the average person. I have found some of your prior posts to be unnecessarily irritating. Tone it down.

Appearance can be modified. A new haircut. Grow a beard (or shave one off). Decide who the new you will be and get an appropriate new wardrobe. All it takes is a few new outfits. Research and try out a few new looks for the new you. People re-invent / re-make themselves all the time.

What is the problem with your hands? Too small? Thin fingers? Deformities? Please explain.

Skill are learned. No one is born with them. Please identify the skills you'd like to improve, e.g., job skills, interviewing skills, social skills, dating skills. Have you sought help improving these skills? If so, how?

Depressive predisposition is sometimes seen as attitude. Do you have an attitude problem? Is your attitude often negative? What are the causes of your depression?

Change is a part of life - an important and necessary part of life. Why are you so inflexible? Why don't you want to become more flexible with the way you live your life? How did you learn to be so obstinate?

If you need to make changes in your life so that you like being alive then you have to learn to be flexible. If a few of the changes work out for the better then you might gain some positive feelings that will help carry you through to additional life improvements. Tell us more.