I have found Effexor XR to be very useful in the past. The only problem I had that made me try something else was when I was off meds and tried to get back on, effexor made me even more jittery and gave me an upset stomach until I was used to it again.
Effexor is one of the only drugs I have ever found useful for anxiety. I did, however, have a strange sensation in the beginning of being wrapped in cotton guaze and my mental alertness was "blunted" but it kind of felt like pot...er, not that I'd know..um..you get the point
But once I was used to it, these more extreme sensations subsided