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Old Nov 10, 2013, 02:27 PM
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rockgal rockgal is offline
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Member Since: Apr 2007
Location: United States
Posts: 112
Quote:
Originally Posted by bipolarchickk View Post
I'm currently on lamictal 200mg, wellbutrin 450mg, topamax 50mg and my mood is CONSTANTLY changing. It can change many times a day. I'm not normally manic, but the depression comes and goes like crazy.. along with anger. Here's some of the other meds I've tried...
Lithium-worst med ever... made me attempt suicide twice
Depakote-worked but gained too much weight
Latuda- went manic and tons of side effects
Geodon-made me sleep non stop
Invega- worked great but gained 50 lbs
Risperidone- also contirubed to the weight gain and decreased my sex drive completely
Gabapentin- had no effect
Abilify- gave me a twitch in my arm

I know meds work different for everyone, but was just wondering if anyone had any suggestions?
any help appreciated, thanks

If your doctor is willing to go outside the proverbial box, ask him/her to look into minocycline. There have been some papers about its ability to help various neurological and psychiatric conditions - there's some theoretical basis, and clinical trials have been undertaken. In particular, there is a 2004 paper exploring whether minocycline has antidepressant effect.

I'm currently having very good luck with it for treatment resistant depression (combined with a low dose of a abilify). The doctor who recommended has had success in at least one other patient, and someone else that I know is finding it helpful.