Sorry to hear you're struggling! For me Prozac was very ineffective, caused weight gain, sexual problems and made me feel numb. I love Welbutrin because it works great on MDD, causes weight loss, no sexual side effects, and is activating. I didn't find much help with CBT, but find DBT rather effective. For insomnia I love, Trazodone with Sonota and Neurontin. Best of luck!