I had severe depression before I tried it too, but to be honest, I was on the upswing. I also had been diagnosed with dysthymic disorder, and had no memory of ever not being depressed. I did feel a lot better after starting SJW, and I keep taking it now, though not always consistently. I can't say that it's absolutely related to taking or not taking SJW (maybe I stop taking it when I feel like giving up for a while), but I have small relapses when I stop taking it.