it can take 2-3 days or even 1-2 weeks for the side effects to disappear. It took a week for me but got better. Also if u were started at 50mg u may want to try splitting that in half to make 25mg, I did that and worked out better for me. Be sure you run this idea by your doctor first! I take Zoloft for the anxiety mostly and worked fine for a while, seems to be getting weaker now for me. I'm at 100mg.