
Hello and welcome to Psych Central! I can understand your worry. It doesn't sound like your son and his wife are communicating very well, and it's sad that she is working somewhere undesireable against your son's wishes.
However, that said, I don't know that you are in a position to get right in the middle of things. It's up to your son to deal with the situation. I suppose you could just express your concern and say, "If there's anything I can do that might help, then please let me know." He is a grown man after all.
And I'm one to talk, since I am a big worrier, but please try not to worry too much. If you are a praying person, then you can pray about it. But if we can't do anything about a situation, then worry is not going to help them or us. Hang in here! Okay?