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Old Nov 16, 2013, 10:25 PM
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nbritton nbritton is offline
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Member Since: Oct 2013
Location: Texas
Posts: 340
Quote:
Originally Posted by monochromatic View Post
I wish there was a way to come down softly so we didn't crash into depression.
There is, you simply taper and stop taking it before you hit mania. I'm still experimenting, but I've found, in myself, that taking 10mg at bedtime, then 5mg at bed time the next night, then 2.5mg at bedtime the next night gets me going without actually inducing mania.

I've been toying with the ideal of doing something like this on a continuous weekly basis, for example: Fridays 10 mg, Saturdays 5 mg, Sundays 2.5 mg. I'm not there yet though, I'm still playing with what times and doses to administer it at. I know if I take 10 mg for more than few days I get wonky. However, eventually I figured out I could extend the effects without going wonky if I tapered it.

I haven't explored why it works, it seems somewhat counter intuitive, as cortisol is lowest at night and highest in the day, by taking the prednisone at night I'm effectively inverting the natural cortisol cycle. Maybe this disruption resets circadian rhythm.