I have been on Seroquel (200 mg) for about 3 years. Haven't had any side-effects and it mainly helps for sleep.

Caution: One time I took this med in the morning by mistake. I didn't realize how powerful it was, went to work, got so drowsy and just about passed out. I took at about 5:00 am and about 6:30, I almost couldn't function. Had to catch a cab home and went to bed. Just started the damn job, they must have thought I was #$@$# up. Hope I didn't scare you.