Hi Jpny, Iremember talking to you when you were going off the efexor. I am so sorry to hear that you are not coping but the sad fact is that maybe you do need to try another AD. I know that is not what you want to hear and I do know how you feel. Trying another AD is a depressing thought in itself, not knowing will it have the desired effect or will the side effects outweigh the benefits. Having a long distance to travel and the expence would put nearly all of us off it, but you can't go on as you are, can you? Best Wishes.