Prozac was my first AD many many years ago, i did put on weight after a time but that,s because my anxiety was helped has well has depression with PROZAC i wasnt burning off calories like when i had anxiety. That is one good thing about anxiety you will never be fat, Prozac actually took 12 weeks to work on me, all that time i was really ill but i stuck with it and one day over night it changed my life . The world suddenly came to life and i was actually happy .