I don't have much to add on the emotional aspect.

I do have this to add though.

About a year ago my grandma got real ill. She had flu-like symptoms. She has a couple of immune-deficiencies and so anytime she gets sick she gets real scared. Well, the flu-like symptoms began to go away and so she started doing a lot more around the house. I think that that caused her to get sick all over, because she wasn't sleeping good and was doing too much. The sickness came back and got worse and worse. It got to the point where she just felt like she was going to pass out, and my grandpa took her to the hospital. In the ER she started blurring her speech, and then started precisely vomiting. They took her to the back, and their initial reaction was that she had a minor stroke "TIA".

Well, when she woke up she still had jumbled speech and one side of her body was weak. Typical signs of a stroke. Yet they ran some tests and turns out it wasn't a stroke at all. They didn't know what happened. They started doing physical therapy, and it wasn't long before she was using a walker in the hospital and getting back to herself.

I went to visit her, and when I got home I got a call. She had suffered from a major stroke. It was bad. One side of her body was completely paralyzed with little movement in the other. You couldn't make out anything she said. It was really hard to see her like that.

Slowly but surely she got some things back. Her voice got better, she regained some movement. They did more tests and guess what? Not a stroke, again they didn't know what happened. They still aren't certain, but they did diagnose her to the best of their abilities. And this may help you.

They said she had a rated disease called "ADEM". It is a disease that normally attacks children. What it is, is a normal illness stays in your body and doesn't go away. It ends up attacking your brain, causing stroke-like symptoms. Some people recover right away, some people never again.

My grandma is a little older than your wife. 58, but she has still not recovered. She needs help to the bathroom, she can't even stand up or get out of a chair by herself. She can walk with a ton of help, but has no balance and the person walking her is doing most of the work. It's been over a year now, and I don't see much hope she will ever regain everything. One of her arms still won't function much, and one of her feet as well. She has violent rages. She will slap, bite, and pinch my grandpa. She will scream at him, call him bad names and accuse him of cheating. Some days she seems normal, some days she acts like she is 5 and even calls my grandpa "daddy". It is very frustrating, so I feel your pain. My grandpa has it much worse than me. I just try to help out around the house, but he always takes care of her and even has hired a caregiver for when he is working. I don't know how he does it and stays sane, I couldn't.

Anyways, might be worth looking into. Perhaps your wife suffered from this as well, just not as severe of a case.