I have been on Seroquel for a number of years. I requested my PDOC but me on Metformin at the same time. I had read that it protects you from getting Diabetes and Metabolic Syndrome that are common side effects with all the new anti psychotics.

It did not stop the weight gain though. I gained 90 pds.

I have just lost 30 pds over the last 4 months by following the Chris Powell diet plan and exercising a little more. I have tried many diets on seroquel and this is the only one that has worked.
It is based on Carb Cycling alternating low carb days with higher carb days.