Have you tried taking SSRI's before? It can make a difference and might help with things like strong feelings of guilt. Especially when I was at my very lowest, Paxil helped me get back some amount of stability. I don't take meds anymore, but they did help me back then. I am really resistant to therapy because I am very private and I like to avoid social situations and emotional connections (aka meaningful friendships, haha), but I am starting the think that would be the only way to really make meaningful progress in my problems...