Hey DJ. My pdoc wanted to take me from 500 to 1000 depakote, but I freaked out since when on lithium after an upped dosage I became toxic. I asked her to go baby steps because I freaked so bad. Guess I should have listened to her and gone to 1000. I am hoping to stop there so I won't have the bulk of the side effects. Thanks for the info. I am just so up and down. I have a hard time waiting for the prize.