herethennow, my current depression started 8/4 without any trigger at all, so I get it. I have explained this to both my pdoc and T. Neither seemed too surprised - - i.e., like it was something they hadn't heard before. My T keeps telling me to use cognitive behavioral approaches, trying to analyze my negative thoughts, or to exercise. I can try to change my irrational, negative thoughts all I want, but it just seems like an exercise in futility(no pun intended). Exercise might distract me briefly or make me feel a littler better with the supposed increased endorphins, but it's short-lived and back to the depression always. This triggerless depression just really seems to have a hold on me and, yes, it's extremely frustrating.

I keep thinking that because there was no trigger, it's got to be biochemical. Well, now I'm on antidepressant #2 since it started. Have only been on a low dose of Prozac (20 mg) for about a week, so it's probably too early to tell if it'll be the magic bullet that propels me out of this.

May I ask which antidepressant you're on (assuming you're on one)?

Also, this has gone on for so long for me too that it seems old hat. At the beginning I had some fight in me, but it just seems no matter what I try to alleviate the depression, nothing works (or very few things). Just know you're definitely not alone.