Yes. It will clear your system faster.

ETA: I see that S.p. already answered this and provided a chart (? - I didn't follow her link). I found a chart once about this too. Couldn't find it again this morning.

Elyn Saks takes 40 mg of olanzapine which is twice the recommend max dose, but she's also a very heavy smoker.

When my son quit smoking last year, his pdoc lowered his dose again in order to adjust for it.