PS: I took Seroquel for awhile for psychotic features and I relate to hating the sedating effect. It was so hard to get going in the morning. I was working at the time and it was such a struggle. I eventually adjusted somewhat - my pdoc took me off the XR version and put me on the non-XR version. That helped some. I know others that have adjusted to the sedating side effect. A woman from my support group takes 1500 mg - I'd be asleep for so long at that dosage! Good luck and keep up posted. x