I have a great interest in evolution. The concept that seemed so simple when discovered , it was a wonder how naturalists had not come across it sooner. The basic principle of evolution by natural selection is that a very simple process could account for so much complexity. Looking at a living animal , it was impossible to fathom how an event could account for such a giant leap. Of course our mental biases saw this as a single event rather than minute steps taken over milions of years. It could well be possible that there is a simple genetic mutation or enviromental phenomenon that could have a knock on effect , on say the , process of embryology , through childhood and onto adulthood. When we come to look at schizophrenia we usually do at its presentation , at which stage the disease has developed beyond its basic pathology , incrementally adding more and more complexity in terms of its definition.

For example there is a hypothesis I read that neuron migration from deep brain, out to the cerebrum in embryology and early childhood could account for the differing and varying symptoms you see in psychotic presentation. Just because the symptoms differ that does not mean there is not a basic underlining pathology at fault. Again how the brain stem , cerebral cortex, hind brain , mid brain fore brain develop , is essential like an opening flower with neuron migration pushing outwards to form the cortex. Such is the complexity and uniqueness of this migration it could well be responsible for all kinds of varying symptoms as characterised by the migration towards and formation of the cortex.

Just an idea.

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