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Old Jan 22, 2014, 10:46 PM
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Sometimes psychotic Sometimes psychotic is offline
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Member Since: May 2013
Location: Chicago
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Quote:
Originally Posted by paulycoll View Post
I was editing my post as you were writing yours. Look at the last paragraph as an example. By knock on effect I mean that a problem with migration could account for all types of complex problems with thought ,perception etc. But the migration itself could be governed by a simple process. Do you get me?

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Oops sorry about that, yep totally get you, had to look it up it's really interesting and for insidious onset sz that's chronic I totally think it's pretty plausible. I guess I tend more for something that can be rapidly changed because I had total functioning one day and then pure hallucination without the chance to even sleep the next day. I know the briefer psychotic disorders are classified differently in the dsm v and the icd-10 but they never seem to be studied because they resolve...the only place they come in is FEP studies and I've never seen any genetic studies or or structure studies on people with only psychosis. I suppose I'm wrong in assuming they have the same mechanism but they pretty much get treated like a baby form of sz because the pdocs have no idea if you meet the criteria unless you have had 6 months of symptoms when they meet you.

Anyway in my grm3 there is just an over abundance of a non-functional splice variant and splicing is easy to change. So I genuinely feel that's what's wrong with me and I wonder if stress can change the splicing of that gene...

I guess my general feeling is that psychosis isn't a single entity I mean there are tons of medical conditions and drug induced psychosis it seems like the drugs they do understand all have different mechanisms.
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