I don't respond well to SSRI's or SNRI's. I'm currently taking a tricyclic AD, imipramine. Tricyclics are older AD's and don't have the side effects of the newer SSRI's and SNRI's I took it in the late 80's and it worked well for me. I may have been hypomanic when I was on it. I'm not sure because I wasn't diagnosed until 2011 with BP2. Now I find that taking it with respiridone and lamictal work much better for me.