Who calls you a loser? Is this a label you put on yourself? When you think of yourself poorly that reflects on to other people. Try to think of yourself as a "winner" rather than "loser", introduce yourself with happy positive vibes, everytime you start to think depressively challenge those thoughts. Talk yourself up on job applications, show off your good traits. Focus on the positive rather than the negative. Some people have to take meds to even be able to survive, does that make them losers? I think not.