When the side effect is more miserable than the disease, itself, there is no way. I was less suicidal before I started them than I was while on them because I just wanted the pain and muscle problems to stop. I can't explain to someone who hasn't felt it how horrible it feels. I have been on over 50+ medications for over two and a half decades for my severe mental illness. I know the difference between minor side effects, moderate side effects and debilitating side effects. In most cases, I can live with even moderate side effects, even expect them, but uncontrollable flailing and thrashing, making it impossible to sleep for days, walk correctly and speak right is a deal-breaker.