Yes, it made me irritable and quick to bite people's heads off who annoyed me. I would also act out in my head that I was arguing with someone and I would imagine myself acting out violently. It went away but came back for a bit after I upped my dose to 300. I ended up quitting it a few weeks ago as I had some other side effects like no libido and urinary issues. I didn't get any great benefit from it apart from weight management. A side note is I was taking generic bupropion. Who knows, maybe the real stuff would have been different.