Zoloft is a great med it turns you brain down a notch , but its nick name is (SOUL OFF) Zoloft get it. So booze is a depressant and you brain in turned down a notch don't sound a good combo . Why take anti depressant on the booze anyway just drink more if you looking for blot out. I used booze has a self medication with no meds but shorts not beer. if you want to get drunk 3ltr bottle frosty jack cider for a few dollars will do it. But I wanted to Obliterate my brain from pain so I drank ltr of vodka straight back it one. Did the job perfect Russian roulette you wake up later or you don't but at least I got an hour of pleasure. THIS was fine till my body gave in, and I am missing several body parts now that died in the pickling process , plus I cannot drink again, my kidneys not my liver witch is strange are f++++d